Matias Vecino scored the only goal as Napoli lost a home Serie A match for the first time since April 10, 2022Serie A leaders Napoli suffered only their second league defeat of the season as they lost at home to Lazio, who moved up to second in the table. Matias Vecino scored the only goal in the 67th minute with an excellent strike from outside the penalty area. Serie A top goalscorer Victor Osimhen, with 19 goals in the league, came closest to an equaliser but saw his header bounce off the crossbar. Lazio’s Sergej Milinkovic-Savic also hit the woodwork with a free-kick. Vecino’s goal was the first goal Napoli had conceded in six games. Napoli are aiming to become Italian champions for the third time with their last success coming in 1990. Despite this loss , they are still in a dominant position as they are 17 points clear of Lazio, who move one point above Inter and AC Milan with the Milan clubs both having a game in hand.AC Milan play at Fiorentina on Saturday before Inter entertain Lecce on Sunday.Line-upsNapoliFormation 4-3-31Meret22Di Lorenzo13Rrahmani3Kim Min-jae17Olivera99Zambo Anguissa68Lobotka20Zielinski11Lozano9Osimhen77Kvaratskhelia1Meret22Di Lorenzo13Rrahmani3Kim Min-jae17OliveraSubstituted forZedadkaat 90+3’minutes99Zambo AnguissaSubstituted forElmasat 71’minutesBooked at 89mins68LobotkaSubstituted forNdombéléat 82’minutes20ZielinskiSubstituted forSimeoneat 82’minutes11LozanoSubstituted forPolitanoat 71’minutes9OsimhenBooked at 63mins77KvaratskheliaSubstitutes4Demme5Nunes Jesus7Elmas12Marfella18Simeone19Bereszynski21Politano23Zerbin31Zedadka55Østigård70Gaetano91Ndombélé95GolliniLazioFormation 4- 3-394Provedel77Marusic4Gabarrón Gil13Romagnoli23Hysaj21S Milinkovic-Savic5Vecino10Romero Alconchel7Felipe Anderson17Immobile20Zaccagni94Provedel77MarusicBooked at 90mins4Gabarrón GilBooked at 21mins13Romagnoli23Hysaj21S Milinkovic-Savic5Vecino10Romero AlconchelSubstituted forCataldiat 88’minutes7Felipe AndersonSubstituted forPedroat 59’minutes17Immobile20ZaccagniSubst ituted forCancellieriat 82’minutesSubstitutes1Arantes Maximiano3Pellegrini6Marcos Antônio9Pedro11Cancellieri18Romero26Radu29Lazzari31Adamonis32Cataldi34Gila88Basic96FaresLive TextMatch ends, Napoli 0, Lazio 1.Second Half ends, Napoli 0, Lazio 1.Offside, Napoli. Amir Rrahmani tries a through ball, but Victor Osimhen is caught offside.Attempt blocked. Matteo Politano ( Napoli) right footed shot from outside the box is blocked. Assisted by Khvicha Kvaratskhelia. Adam Marusic (Lazio) is shown the yellow card for a bad foul. Giovanni Simeone (Napoli) wins a free kick in the defensive half. Foul by Adam Marusic (Lazio).Substitution, Napoli. Karim Zedadka replaces Mathías Olivera.Foul by Giovanni Simeone (Napoli).Matteo Cancelieri (Lazio) wins a free kick on the right wing.Sergej Milinkovic-Savic (Lazio) hits the right post with a right footed shot from outside the box from a direct free kick. Eljif Elmas (Napoli) is shown the yellow card for a bad foul. Foul by Eljif Elmas (Napoli). Matteo Cancel ieri (Lazio) wins a free kick in the attacking half. Substitution, Lazio. Danilo Cataldi replaces Luis Alberto. Tanguy Ndombélé (Napoli) wins a free kick in the defensive half. Foul by Ciro Immobile (Lazio). Attempt blocked. Matteo Cancelieri (Lazio) left footed shot from outside the box is blocked. Assisted by Sergej Milinkovic-Savic. Tanguy Ndombélé (Napoli) wins a free kick in the defensive half. Foul by Sergej Milinkovic-Savic (Lazio).